Prevalence of Hypertension and Diastolic Dysfunction with Type-2 Diabetes Mellitus

Abstract

ackground: left ventricular diastolic dysfunction is common in patients with type 2diabetes mellitus, but their prognostic importance in these patients remains unknown. Aimof this study is to detect the association of hypertension and diastolic dysfunction (LVDD)with normal ejection fraction in type-2 diabetes mellitus.Method: A cross-sectional study of 164 diabetic patients visit diabetic clinic in marjan teachinghospital (76 females and 88 males) from January 2007 to February 2008 were enrolled in thisstudy. Their ages ranged from 35 to 65 years with mean age of 55 years. The inclusion criteriawere: diabetes mellitus type 2, hypertension (BP ≥ 140/90 mmHg) with or without medication,body mass index 30, and waist-hip ratio > 0.90. In those patients we do blood sugar, HbA1C, lipidprofile, ECG, CXR & ECHO to detect Left Ventricular Diastolic Dysfunction (LVDD).Result: Out of 164 patients, 80(48.7%) were found to be hypertensive (both systolic and diastolic)and 9 patients (5.3%) were found to be suffering from isolated systolic hypertension. Hence, totalnumber of hypertensive patients was 89 (54%). Twenty five out of 164 patients were found to besuffering from diastolic dysfunction with normal ejection fraction.Conclusion: Hypertension and Diabetes are interlinked and show how micro and macrovascularcomplications of diabetes are increased when two conditions occur together. The LVDD is muchmore prevalent than previously suggested in patients with type-2 diabetes mellitus. Hence, LVDDis an early marker of diabetic cardiomyopathy.