EFFECT OF ADDING JERUSALEM ARTICHOCKE INULIN IN DIETS ON MICE SERUM CHOLESTEROL AND LIPIDS

Abstract

Inulin was extracted from local Jerusalem artichocke and was added to mice diet at levels of 2.5 and 5% (T1 and T2) respectively, beside group three (T3) which was given 5% crude inulin powder .Results were compared with control group (Tc) no inulin in diet .The level of liver lipids decreased significantly (p<0.01) to 0.78 and 0.64% for the treatments T2 and T3, respectively, compared to T1 and Tc which contained 2.17 and 2.43 % lipids, respectively. The fresh intestinal weight for T1, T2 and T3 were 1.96, 2.42 and 2.16 respectively , which were all significantly (p<0.01) higher than 1.48 gm for the Tc. The number of lactic acid bacteria present in intestine for the T3 were 9.4×108 (cfu/ml) which was significantly (p<0.01) higher than the number found in intestine for T2, T1 and Tc which were 8.6×108, 8.2×108 and 7.9×108 (cfu/ml), respectively. The number of bacteria for T3 was significantly (p<0.01) higher than other treatments. There were significant (p<0.01) differences in cholesterol and triglyceride TG content of blood serum among treatments. The level of total cholesterol and LDL decreased significantly (p<0.01) among treatments T3(121.5, 20.7), T2(132.3, 38.7), T1(140, 44.8) respectively compared to the control Tc(143.5, 47.8) mg/dl. While treatment T2 had the lowest value for TG (115) and VLDL (22.2) mg/dl compared to T1 (121) and VLDL (24.8) mg/dl. Treatment T3 had significantly lower value (126) for TG and (25.2) mg/dl for VLDL compared to control Tc and (131.5) for TG and (26.3) mg/dl for VLDL. The good cholesterol HDL had the highest level in T3(75.6) followed by T2(71.4) then T1(70.4) in comparison to Tc (69.4) mg/dl respectively.