Influence of Sperm Concentration, Morphology, and Motility on The Result of Intracytoplasmic Sperm Injection

Abstract

Defective Sperm parameters was suggested to play an important role in determining fertility and was proven to be closely related to fertilization and pregnancy rates in the natural fertilization process as well as in ART.To evaluate the influence of defective sperm parameters including concentration, morphology and motility on intracytoplasmic sperm injection outcome represented by fertilization rate, cleavage rate, embryo quality and pregnancy rate.This a cohort study included 60 infertile couple attended the clinics of infertility treatment center Al-Sadder teaching hospital and underwent intracytoplasmic sperm injection. They are classified into three groups according to their spermiogram and ICSI outcome evaluated for each group and compared with each other.The main results of this study showed no significant difference in fertilization rate,cleavage rate ,embryo quality and pregnancy rate among studied groups i.e., no significant difference in ICSI outcome between normozoospermic group and those with defective spermiogram. Intracytoplasmic sperm injection outcomes represented by fertilization rate, cleavage rate embryo quality and pregnancy rate were identical with no significant differences between couples with defective sperm parameters and those with normal spermiogram.