Relationship Between Leptin and Thyroid Hormones In Type 2 Diabetes Mellitus Patients


This study was performed in the Diabetes and Endocrine Center at Al-Husain Teaching Hospital. The patients and control groups were with age ranged between (40-83) years. Study was carried out on 60 patient with type 2 diabetes mellitus (28male and 32 female) and 20 apparently healthy subjects male and 20 female how dealt with as control group. Leptin and thyroid hormones(T3,T4, AND TSH) measurements were carried out using ELISA technique. Both patient and control groups were classified according to obesity, age, and gender . Results of the present study show that leptin hormone was significantly high in serum of type 2 diabetic patients group compared with control group (P < 0.001).also there was a significant gender difference (female more than male) and significant positive correlation with body mass index and body fat . Results also show that TSH hormone and FBS were significantly high(P < 0.000), while T3and T4 decrease significant(P < 0.000) in type 2 diabetic patients group and compared with control group.