The use of Spectrophotometric Batch and Flow injection Estimation of Clonazepam drug in Pure and Pharmaceutical Preparations

Abstract

Two simple, sensitive, accurate, and rapid spectrophotometric batch and FIA methods have been developed for the estimation of clonazepam in pure and in a commercial tablet pharmaceutical preparations. They are based on the oxidative coupling reaction of clonazepam (CZP) with Resorcinol in the presence of sodium periodate exhibiting red coloured products obtained with a maximum absorbance at (