Addition Reactions of Some Schiff’s bases of Isatin

Abstract

Schiff’s base of isatin were prepared by condensation isatin with primary amines and products were considered as nucleus then reacted with acetyl chloride, benzoyl chloride and chloro acetyl chloride in dry benzene as a solvent to afford addition products ,then the resulting chlorinated amides were reacted with thiourea compounds in the presence sodium carbonate (Na2CO3) and absolute ethanol as a solvent to afford thioureas compounds ,All the prepared compounds were identified by infrared spectroscopy (IR) and by 1H.nmr and 13C.nmr spectroscopy and C.H.N.S analysis for some of the prepared compounds.