The IHC Expression of IL-13 in Bladder Tumour

Abstract

The study designed to detect IL-13 expression in bladder tumor tissues , and to clarify the relationship between itsꞌ expression and clinicopathological grade of bladder cancer . The expression of IL-13 in tumor cells was investigated in (50) patients with urinary bladder carcinoma (UBC) of different grades (G) and (15 ) patients with urinary bladder diseases benign tumor (UBD) from three Hospitals in Baghdad Province . The tissue sections were analyzed immunohistochemically (IHC) to detection of IL-13 . The results showed a high positive immunohistochemical IL-13 expression of UBC tissues than in UBD tissues (86 % versus 26.7% ; p≤ 0.01) . Also ,the high grade of UBC patients was significantly associated with IHC expression of IL-13 (p≤0.01). We concluded the higher expression of IL-13 in the bladder cancer patients suggests that is involved in progression of tumour.