Detection of white mice intestinal immune response against the external surface of Hymenolepis nana by scanning electron microscope


The aim of the study was involve the scanning electron microscope to detect any damage to the surface of the Hymenolepis nana worm at different ages due to host intestinal immune response. Fifteen male albino Balb/c mice were used in this experiment. The eggs suspension obtained from gravid proglottid was given to mice by administration tube. The infected mice were killed at different intervals. The intestines of mice were opened and the worms allowed to release. These worms were examined by electron microscope. The results as observed; the surface of the scolex has a smooth structure in both 30 and 63 days old worm. The neck surface was smooth at 10 days and at the 30 and 63 days old worms was pitted. There were puff-like cells attached to the surface; these were lymphocytes, and may be eosinophil. Similar damage was seen on the tegument of posterior part of the worm. We can conclude that there is a progressive destruction of tegument as worm ages, and this is believed to be a consequence of immune response.