Synthesis of New 10-Amido phenoxazine Derivatives

Abstract

This work includes synthesis of new phenoxazine derivatives containing N-substitutedphenoxazine starting from phenoxazine (1).10-nitrosyl phenoxazine was prepared through thereaction of phenoxazine with sodium nitrite to give compound (2), which reacted with zinc inacetic acid to give 10-amino phenoxazine (3). Condensation of compound (3) with benzoylchloride, isovaleryl chloride and 4-bromophenacyl chloride gave 10-amido phenoxazinederivatives (4-6).