Determination of Homocysteine and Vitamin B12 level in blood Patients Rheumatoid Arthritis in KirKuk Governorate

Abstract

Many of the clinical studies have clearly demonstrated the direct link between the high levels of homocystien in serum and Rheumatoid Arthritis and homocystien shows its impact by imbalance self- oxidized when high concentration in blood, which leads to a group of deeply rooted Free radicals and Rheumatoid Arthritis RA of Disease Fades inflammatory caused by free roots which cause injury to the damage or the total deficit circumstantial there are some features may occur to the formation of a contract of rheumatic smalObjective:. The aim of this study to assess the level of homocystien and vitamin B12patients suffering from Rheumatoid Arthritis compared with healthy people and operate in order relationship with vitamin B12 and its impact causing high levels of homocystien disease Rheumatoid ArthritisThe way:- collecting blood samples (25) people healthy people (Control) (15) of the males and 10 females aged from (25-65) and (50) people of the patients (25) of the males and (25) of the females aged from (25-65) and those suffering from Rheumatoid Arthritis and measurement of the level of homocystien and vitamin B12.The findings and conclusions:- found that there is a moral rise in the level of homocystien when a group of patients suffering from Rheumatoid Arthritis compared with healthy group at the level of contingent liabilities (P≤0001) found moral decline in the level of vitamin B12 when a group of patients suffering from Rheumatoid Arthritis compared to a healthy and at the level of contingent liabilities (P≤0.0005).Word: homocystien , vitamin B12 , Rheumatoid Arthritis