Synthesis and Characterization of New heterocycles compounds derived from coumarin


7-hydroxy-4-methylcoumarin was synthesized by the reaction of resorcinol with ethylacetoacetate, then reacted with chloroacetone and acetic anhydride to give 4-methyl-7-(2-oxopropoxy)-2H-chromen-2-one and 7- Acetoxy -4-methyl-coumarin.New derivatives of chalcone were synthesized by the reaction of 4-methyl-7-(2-oxopropoxy)-2H-chromen-2-one and 7- Acetoxy -4-methyl-coumarin with substitutedbenzaldehyde in presence of potassium hydroxide.Acid hydrazide synthesis from reaction of ethyl cyanoacetate with hydrazine hydratealso acid hydrazide was reacted with compound 4-methyl-7-(2-oxopropoxy)-2Hchromen-2-one to give compound (11), then compound (11) reacted with salicylaldehydeand 5-bromosalicylaldehyde to obtain coumarin derivatives (12-13). The new compoundswere characterized by some spectroscopic methods (FT-IR spectroscopy, 1H-NMRspectral and GC-Mass) and determination of their physical properties such as meltingpoints.