The effect of cigarette smoking on some blood parameters, blood pressure and renal function test.

Abstract

This study investigated the effect of cigarette smoking on some hematological test profiles which comprised of complete blood count (CBC) and blood preasure, heart rate and renal function test including blood urea nitrogen (BUN), serum creatinine (Scr). The study included 60 males from students and the staff at Basrah University's: (30) smokers and (30) nonsmokers aged 20-49 years old. The results Showed that white blood cell counts WBC was significantly higher (p<0.05) in 20-49 years of age smokers group compared with nonsmokers group , red blood cell RBC counts , hemoglobin (Hb) and hematocrit (Hct) were significantly higher (p<0.05) in 30-49 years of age smokers group compared with the same ages of nonsmokers, mean corpuscular volume (MCV) was significantly increased (p<0.05) in 20-49 years of age smokers compared with control group, while mean corpuscular hemoglobin concentration (MCHC) was significantly lower in 30-49 years of age smokers compared with the same ages of nonsmokers , but no changes significant in mean corpuscular hemoglobin (MCH) and platelet (Plt) count were observed in all age groups (p<0.05). The results Showed that Lymphocytes (Lym) was significantly higher (p<0.05) in 20-49 years of age smokers compared with the same ages of nonsmokers, eosinophils (Eosi) was significantly higher (p<0.05) in 40-49 years of smokers compared with the same ages of nonsmokers . The neutrophil (Neut), monocyte (Mono) and basophil (Baso) showed a non-significant changes in all age groups ((p<0.05) ). Whereas systolic and diastolic blood pressures and heart rate showed a significant increases in the 30-49 years of age smokers compared with the same ages of nonsmokers, serum creatinine (Scr) and blood urea nitrogen (BUN) were significantly higher (p<0.05) in 20-49 years of age smokers compared with the same ages of nonsmokers. The study aims to identify the impact of cigarette smoking on some hematological test profiles which comprised of complete blood count , blood pressure, heart rate and renal function test.Conclusion: The cigarette smoking causes significant higher increases in WBC, RBC, Hb,Hct,,MCV , Lym and Eosi. count Significantly lower in MCHC ,while no significant in MCH, Plt,, Neut, Mono and Baso. Also there was a significant increases in systolic and diastolic blood pressure, heart rate, serum creatinine and blood urea nitrogen