Contrast Induced Nephropathy In Diabetic And Non-Diabetic Patients Underwent Percutaneous Coronary Intervention In Erbil City

Abstract

Background: Since the advent of coronary angioplasty more than 3 decades ago, the volume of percutaneous coronary interventions has been rising progressively. Contrast medium was used in diagnostic coronary angiography and percutaneous coronary intervention. The use of iodinated contrast medium is a common precipitator of contrast-induced nephropathy.The objective of this study was to evaluate the incidence for the development of Contrast induced nephropathy in diabetic and non diabetic patients underwent percutaneous coronary intervention which was not studied in Erbil before.Patients and methods: One hundred twenty five consecutive patients,64 diabetic and 61 non diabetic underwent Percutaneous coronary intervention were included in this study which was conducted in Erbil surgical specialty center in Erbil. The renal function has been assessed before the procedure , 24hours and 1 week post procedure.Results: The incidence of contrast induce nephropathy was 5.6%(7patients) one day and 13.6% (17patients) one week post procedure. There were a statistically significant association between development of contrast induce nephropathy in diabetic patients (P value<0.001), non-diabetic (P value 0.001). hypertensive patients (p value 0.03), ,contrast volume (P value 0.001),those who receieved intravenous fluid (p value 0.01) . Comparing diabetic with non-diabetic group there were a statistically significant association between volume of contrast in diabetic group (p value 0.001) and non-significant association with the non-diabetic group (p value 0.1).Conclusions: Contrast induce nephropathy is an important complication developed after percutaneous coronary intervention and ,it is more in diabetic patients .