A Correlation Study Prolidase Activity and Lipid Profile in Sera of Patients With Cardiac Diseases

Abstract

Cardiac diseases were the main causes of different biochemical changes which mostly leads to death in over the world. This study was aimed to study the correlation between prolidase activity and heart diseases. Eighty five sera samples (male and female) sera samples (male and female) for patients with heart disease were collected from the center of heart diseases in Erbil. As a control group 45 samples of healthy individuals were collected The level of prolidase activity, Lipid profile [Total cholesterol, , High density lipoprotein- Cholesterol (HDL), Triglycerides (TG), Low density lipoprotein- cholesterol (LDL-C) and very low density lipoprotein (VLDL)] were determined in sera of groups under investigation, and the results showed: The levels of Prolidase activity cholesterol, triglycerides, VLDL and LDL-C were significantly increased in sera of patients with Cardiac disease as compared with control group. While the HDL-C decreased significantly (p≤0.05) in sera of patients as compared with controlled group.Prolidase was positively correlate with total cholesterol, triglycerides, HDL-C and LDL-C in sera of patient group.