Hemophagocytic lymphohistiocytosis (HLH)

Abstract

Hemophagocytic lymphohistiocytosis (HLH This aggressive and potentially life-threatening disease most often affects infants from birth to 18 months of age, but cases in older children and adults have been reported. We describe a 14-year-old boy whom (HLH) developed. He suffered from fever with disturbed level of conciseness. Physical examination revealed drowsy but easily arousal, pallor, no cyanosis, no jaundice, faint macular rash, soft distended abdomen, and hepatomegaly. Laboratory findings were abnormal liver function, coagulopathies, hypertriglyceridemia, high renal indices, urinalysis show hematuria and proteinuria, anemia, thrombocytopenia, high serum ferritin level and abnormal bone marrow findings.