Effect of laparoscopic ovarian drilling (LOD) in treatment of polycystic ovarian syndrome (PCOS)

Abstract

Background: Laparoscopic ovarian drilling (LOD) has been widely used to induce ovulation in women with polycystic ovarian syndrome (PCOS), but still there is considerable controversy about its effect.Objective: To evaluate the effectiveness of laparoscopic ovarian drilling in women with polycystic ovarian syndrome and to note clinical outcome. Methods: A prospective study has been carried out in AL-Yarmouk teaching hospital, Abu-Greab General hospital and Private hospitals. From August 2011 to April 2015, 95 women with polycystic ovarian syndromewere diagnosed and treated by LOD after failure of medical treatment and compared the result before and after LOD.Results: After LOD, 58 out of 95 patients were ovulated with overall ovulation rate was 61%. Twenty (34.48%) out of 58 women had a conception without additional treatment. The LH: FSH ratio, mean serum concentration of LH and testosterone and free androgen index decreased significantly after LOD and remained low during the follow-up periods. Conclusions Laparoscopic ovarian drilling was a safe, effective surgical technique, and widely accepted as the preferred second line of treatment in PCOS.