Evaluation Relationship between IL-10, IL-1α in Hepatocellular Carcinoma Patients

Abstract

The presence of a high concentration of Interliukin-10 (IL-10) In the serum of patients with tumors It is harmful to the health of the injured useful for tumor And that because of its inhibitory properties of the immune response, and perhaps IL-10 works as a growth or a catalyst in stimulating the growth of cancer cells, the study aims to investigate IL-1α levels, IL-10, and evaluating the relationship between them in patients with liver cancer, samples were collected from the educational tumors National Hospital and Al-amal for the treatment of tumors / Baghdad, for the period from 25/07/2015 until 25/2/2016, taking as 5 cm 3 of venous blood of patients with primary liver cancer was 30 and secondary liver cancer was 20 were appointed before the treatment was up a set of secondary liver cancer after taking four doses of chemotherapy, and were compared to a group control of 20, the method is used by linked immunosorrbent assay (ELISA) to measure the level of cytokine, results showed the highest IL-1α levels, IL-10, at the level of probability p <0.01 between groups study, compared with the control group and there are no significant differences between groups The study, the study showed no significant differences among groups of secondary liver cancer before and after treatment.