Synthesis and characterization of new complexes of schiff bases derived from "sulfanilamide" with metal ions Hg+2, Zn+2 and evaluation their biological activity

Abstract

A new four Schiff bases synthesized by the condensation of the aromatic aminecompound: 4-amino benzenesulfonamide with the four aromatic aldehydecompounds: 4-chloroBenzaldehyde, 4-BromoBenzaldehyde, 4-HydroxyBenzaldehydeand 4-(N,N-dimethyl) aminoBenzaldehyde, Also a complexes of pervious ligands weresynthesized with the metal ions with molarity ratio (1:2) M:L. The synthesizedcompounds were characterized by physical and spectroscopic measurements (IRspectrum and proton NMR spectrum, elemental analysis C.H.N, Molar conductivity).All the synthesized complexes were formed tetra-coordinate complexes and thesupposed chemical formula of the consequent complexes:[M(L)2Cl2]. The Biologicalactivity were evaluated for the synthesized compounds against two types of bacteriaE.Coli and S.aureus, most of complexes shown anti-bacterial activity.