Association between the genotypes of gene polymorphisms and certain risk factors of transitional urinary bladder cancer

Abstract

Risk factors play an important role in the development of cancer, especially bladder cancer, as it some factors such as age , sex , housing ,smoking, family history of cancer ,grade disease ,other bladder diseases, were predispose for the increasing incidence and recurrence of bladder cancer. The blood sample were collected from AL-Hussein teaching hospital and AL- Safeer hospital in holy Karbala province that clinically diagnosed and apparently healthy individuals as a control group. DNA was extracted from blood samples, and the presence of polymorphism was detected in the studied genes using advance molecular techniques . The study showed the correlation between some genotypes of the studied genes and the risk factors.