Synthesis of new pyrazoline and oxazoline Derivatives From Indole

Abstract

The objective of the present work is preparing of new pyrazoline andoxazoline derivatives by reaction of amine derivative(4-aminoacetophenone) with Indole, then complete with next step whichinclude the reaction of the product in the first step with somebenzaldehyde derivatives to form chalcones , The final step which includeformation cyclization to prepared chalcones to yield pyrazoline andoxazoline derivatives. The structures of the synthesized compounds areestablished by Elemental Analysis and several technique (TLC, M.p , andIR spectra).