Synthesis of some new compounds derived from 4-hydroxy-3-methoxybenzaldehyde with study of biological activity for some of them

Abstract

The vanillin was converted to ethyl-2-(4-formyl-2-methoxyphenoxy) acetate (A1) by the reaction of vanillin with ethylchloroacetate in basic media in dry acetone.The 2-((4-hydazonomethyl)-2-methoxyphenoxy) acetohydrazide (A2) was synthesized by the reaction of (A1) with hydrazine hydrate, ethanol absolute gave a hydrazide compound, from the hydrazide we synthesized series of compounds (Oxadiazole, Triazole, Aziridine, Schiff’s bases and other derivative compounds). These compounds were identified by T.L.C(thin layer chromatography)., M.P(melting point)., FT(fourier transform).IR, H-NMR and elemental analysis (C.H.N.S).