The possible cancer risk factor of Helicobacter pylori infections in immunocompromised children

Abstract

The frequency of Helicobacter pylori in children with malignancy was evaluate in the present study. Among 51 children included in the study ,29 of them are in malignancy group (79.3% of them having positive one step diagnostic test) ,while 22 children were control group (54.5% of them having positive one step diagnostic test). H.pylori infection was significantly higher in the malignancy group compared to the control group(P<0.05) ; 44.8% having positive culture for H.pylori ,while only 18.2% of control having positive culture for H.pylori. the results showed that there is no significant association between H.pylori and the type of cancer with P > 0.05. And there is a significant association between H.pylori and age more than 5 years with p< 0.05 which is statistically significant among patient groups. results also showed that there is no significant association between H.pylori and sex among both patients and control groups with P> 0.05.