Prevalence of Plasmid-Mediated Quinolone Resistance Genes (qnr) in Clinical Isolates of K. pneumoniae in Najaf


Introduction: The main purpose of this study was to investigating the presence of qnr-genes among clinical isolates of K. pneumoniae recovered from Najaf hospitals. Material and methods: A total of 1590 clinical specimens were obtained from three main hospitals. The Klebsiella spp. were identified by traditional biochemical tests, and confirmed by API 20E system.Theisolates that exhibited reduce susceptibility to quinolones were examined for the presence of PMQR qnr (qnrA, qnrB, and qnrS qnrC, and qunD). Results: The qnr genes were detected in 20 (63.5%) isolates qnrB, qnrA and qnrS were identified in 17 (23%), 2 (2.7%) and 1 (1.4%) respectively. Conclusion: K. pneumoniae isolates harboring PMQR are currently widely distributed in Najaf hospitals.