Efficacy of Rotavirus Vaccination in Prevention of Hospital Admission of Gastroenteritis among Children Under Two Years of Age

Abstract

ABSTRACT:BACKGROUND:Rotavirus is the most common cause of acute gastroenteritis in children. OBJECTIVE :To find out the efficasy of rotavirus vaccine in prevention or reduce the number of cases and hospital admission of gastroenteritis among children under two years of age.PATIENTS AND METHODS:A cross-sectional study was conducted in Central Teaching Hospital of Pediatric in Baghdad,from the first of February to 31st of May 2016,on a total of(524) child under two years of age, grouped into two groups,first group(260)vaccinated with rotavirus vaccine,second group(264)non-vaccinated.RESULTS:According to development of gastroenteritis and vaccination state of rotavirus vaccine,the acute gastroenteritis in non-vaccinated group was more compared with vaccinated group,192out of264(72.8 %)and128 out of 260(49.2%) respectively,and this association statistically significant.The number of cases that is admitted to hospital is48(37.5%)in vaccinated group with acute gastroenteritis which is significantly lower as compared to148(77.1%)in non-vaccinated group with acute gastroenteritis.This study showed that males and females were found to be equally affected of gastroenteritis.CONCLUSION:Rotavirus vaccine have reduced the number of cases and hospital admission of gastroenteritis among children under two years of age in Central Teaching Hospital of Pediatric in Baghdad.