OXIDANT-ANTIOXIDANT STATUS IN POSTMENOPAUSAL OSTEOPOROTIC WOMEN IN DUHOK CITY

Abstract

ABSTRACTBackground and Objectives:which leads to increase bone fragility and fractures. Current studies proved that oxidativestress (OS) has involved in bone resorption. Thus, this study aimed tolevels of oxidative stress parameters between postmenopausal women with osteoporosis andwithout osteoporosis to show whether there is a relationship between oxidative stressparameters and bone mineral density (BMD) orSubject and Method: In this crosswho visited Duhok Rheumatoid Center and performed bone densitometry were enrolled. Astudy questionnaire was used to collect the required information from participants. Serummalondialdehyde (MDA), ceruloplasmin (CP), peroxynitrite (PN), total bilirubin (TBIL)calcium and vitamin D (VD) were studiedResults According to world health organization (WHO) criteria, normal BMD wasdetermined in 12% of the study population, women w36% of women were identified as having OP. Women with OP had significantly higher meanvalues of MAD, PN and CP as compared to controls. Mean values ofremained unchanged. Similarly, VD showed no significhigh prevalence of VD deficiency among the study population. This study showed a negativesignificant correlation between total BMD, lumbarwomen with OP.