Hematological profile of patients with Acromegaly in Iraq

Abstract

Background: Acromegaly is a disease characterized by growth hormone and insulin like growthfactor hypersecretion due mostly to pituitary somatotropic adenoma. The diagnosis ofAcromegaly is usually delayed for years exposing patients to slowly evolving chroniccomplications.Objectives: To explore the value of performing peripheral blood examination as routine work upin monitoring Iraqi patients with Acromegaly.Patients and Methods: This study was conducted on 38 patients with Acromegaly attending thenational center for diabetes research and management. Peripheral blood indices were done byhematological analyzer and blood film stained by Gemisa stain for proper cells morphology doneat hematological unit in Iraqi center for cancer and genetics research.Results: The patients examined showed higher values compared with control group in plateletsindices (MPV and PDW) that were statistically non-significant. The monocyte count wassignificantly lower in patients compared by control group (p <0.05).Two patients were found tosuffer from thrombocytopenia. One male with mild thrombocytopenia, the second is female withmoderate thrombocytopenia. One female with moderate iron deficiency anemia.Conclusion: Peripheral blood exam in patients with Acromegaly is highly indicated, low cost andvaluable in follow up patients.