Prevalence of gestational thrombocytopenia and its effect on maternal and fetal outcome


BACKGROUND: Gestational thrombocytopenia (GT) is considered as the most common cause ofthrombocytopenia in pregnancy and accounts for about 75% of cases.OBJECTIVES: The objectives of the study are (1) to estimate the prevalence of GT among antenatalpatients at Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital in New Delhi, India,and (2) to study the fetomaternal outcome in mild, moderate, and severe GT.MATERIALS AND METHODS: This is a prospective observational study done in the Departmentof Obstetrics and Gynaecology, VMMC and Safdarjung hospital in New Delhi, India, for a period of6 months. All antenatal women underwent complete hemogram with manual platelet count in thethird trimester. Those with platelet count 150 × 109/L were included and divided into three groupson the basis of platelet count. Maternal and fetal outcome was observed. Cord blood was sent forneonatal platelet count. Follow‑up was done in these cases till 6 weeks postpartum.RESULTS: The prevalence of GT was 12.82%. Fetomaternal outcome was favorable. A totalof five (2.5%) patients suffered from abruption. Postpartum hemorrhage was present in about7 cases (3.5%). Blood transfusion including platelet transfusion was needed in around 13 cases (6.5%).There was no maternal mortality. Only 6 (3%) neonates were having thrombocytopenia (plateletcount < 150 × 109/L) regardless of degree of maternal thrombocytopenia. Twenty‑six (13%) neonateswere admitted in nursery for monitoring; among these, 11 (5.5%) neonates’ ventilation was needed.There was no neonatal death.CONCLUSION: Better fetomaternal outcome is seen in GT, so a vigilant and careful monitoring canprevent any adverse event.