High sensitive CRP as a predictor of Coronary Artery Disease Severity on Coronary Angiography

Abstract

Background: Inflammation in the arterial intima has the main role for the pathogenesis of atherosclerosis. Objective: To determine the correlation between serum hsCRP levels and severity of coronary artery disease in a sample of patients referring to Surgical specialty Hospital- Cardiac center in Erbil City 2018.Patients and Methods: In this cross sectional study 120 patients (78 male and 42 female patients) were studied who had undergone coronary angiography procedure among them 80 patients ( 57 male and 23 female ) had Coronary artery disease and the remain 40 patients had normal coronary angiography result. The blood samples from (120) patients were taken and transferred to the laboratory after clotting hsCRP was measured using cobas automated assay.Results: Here we detected a significant difference in the level of hsCRP between patients with coronary artery diseases and patients with normal coronary artery on angiography in addition to that fact the association for the severity of coronary artery disease and hsCRP level between single, two vessels and three vessels diseases, was statistically significant as well a finding which was comparable with other studies that detected a significant difference between hsCRP among patients with more severe coronary artery lesions.Conclusion: The study concluded that high level of hsCRP is a predictor of atherosclerosis and is wise to be done for patients as a risk factor and it is not only a predictor of coronary artery disease but it predicts it is severity as well.