Determination of IL-6 and CRP in Patients with Type Two - Diabetes Mellitus in Baghdad/Iraq

Abstract

Diabetes mellitus (DM) type Two is a major worldwide health problem leading to an increase mortality and serious morbidity. Immunological disturbances involving the cell mediated immune system and improper-lymphocyte function contributes to the path physiological of type Two- DM. The study consist of 50 subjects, ages ranging between (15-85) years who attended to Al-Kazimaih medical hospital in Baghdad/Iraq which divided in to two groups; the first group consists 35 patient (20 females and 15 male) and the second 15 (5 female and 10 males) normal healthy as a control. The patients with type Two -DM were detected for IL-6 and CRP markers so as for control by ELISA test and agglutination test respectively. The results revealed that’s no significant differences (p≥0.05)between the level of CRP in patients type Two- DM and level of CRP in control. So as there were significant differences (p≤0.05) between the levels of IL-6 concentrations in type Two- DM and control represented by increase of IL- 6 in control than in patients. This study aimed to assess and compare the level of serum IL-6 and CRP in patient of type Two- DM in Iraqi patients in Baghdad city.