Synthesis, characterization Some new derivatives from 6-chloro-2-phenylquinoline-4-carboxylic acid

Abstract

This research includes the preparation of thirty four new derivatives of 6-chloro-2-phenylquinoline-4-carboxylic acid , and these derivatives were characterized by their melting point (C.H.N.S) Analysis , (1H-NMR) spectrum, mass spectrum, (FT-IR) spectrum. The synthesized compounds were divides into :-1- Preparation of 6-chloro-2-phenylquinoline-4-carboxylic acid2- Preparation of 6-chloro-2-phenylquinoline-4-carboxyl chloride3-- Preparation of ethyl 6-chloro-2-phenylquinoline-4-carboxylate4- Preparation of 2-(6chloro-2-phenylquinoline-4 carboxamido)benzoic acid5- Preparation of N-acetyl 6-chloro-2-phenylquinoline-4-carboxamide6- Preparation of 6-chloro-2-phenylquinoline-4-carbohydrazide