Determining the effectiveness of Collagen and its therapeutic role in the immunological standards for laboratory animals induced by Pseudomonas aeruginosa

Abstract

The study was conducted in the laboratories of the Department of Food Science, College of Agriculture, Animal House, College of Veterinary Medicine, University of Tikrit for the period from 15 April to 22 May 2018, in order to determining the effectiveness of Collagen and its therapeutic role in the immunological standards for laboratory animals induced by Pseudomonas aeruginosa, as well as measuring the weights of some internal organs (heart, brain, liver, kidneys, spleen, and thyroid). The results showed that oral administration of standard and laboratory chicken collagen did not cause a significant change in the relative weights of the internal organs (heart, liver, kidneys, and thyroid gland), but it caused a significant decrease in the total number of granulocytes. While there was a significant increase in the percentages and numbers of lymphocytes, it was also found that oral administration of collagen caused a decrease in the levels of immunoglobulins IgG, IgM and IgA.