Effect of Salicylate On Fusidic Acid and Ciprofloxacin MICs in Staphylococcus aureus

Abstract

The susceptibility of five isolates of Staphylococcus aureus which isolated from wound infections were determind against ciprofloxacin & Fusidic acid .The findings have shown that ciprofloxacin & Fusidic acid were highly effective on S. aureus isolates when the Minimum Inhibitory Concentration (MIC) was very low .Then the effect of salicylic acid on the MICs for these antibiotic was studied . Salicylate was shown to increase the resistance among S.aureus isolated when the Minimum Inhibitory Concentration (MIC) was very low . Then the affect of salicylic of acid on the MICs for these antibiotics was studied . Salicylate was shown to increases the resistance among S.aureus isolates to Fusidic acid & Ciprofioxacin .