Hemodialysis Effect in Myeloperoxidase Activity and Number of Biochemical Parameters in Blood Serum of Chronic Renal Failure Patients in Nineveh Governorate

Abstract

This study was conducted in Al-Salam Teaching Hospital in Mosul for the period from the beginning of February 2018 to the end of June 2018, and this study aims to assess the effect of hemodialysis in the activity of the myeloproxidase enzyme and number of biochemical parameters for chronic renal failure patients who are undergo to hemodialysis, and this study included follow-up 95 patients with Chronic renal failure at the age of (15-65) years, and different parameters were compared with the same parameters in 30 healthy people who did not have any disease and the same ages as a control group. A significant increase was achieved at the probability level (P ≤ 0.05) in the activity of the enzyme before and after dialysis, compared with the control group. results showed a significant decrease (P≤ 0.05) in iron concentration and total iron capacity in iron associated with patients before and after dialysis compared with the control group. The results showed a significant increase in the activity of the enzyme myeloperoxidase in the age group (31-40), and the concentrations of Urea, Creatinine Uric acid, and decrease in Iron concentration of Iron and TIBC as a result of the effect of age.