Value of Strain Ratio in the Assessment of Solitary Thyroid Nodules

Abstract

BACKGROUND:Ultrasound elastography (UE) is widely used in the diagnosis of thyroid diseases.OBJECTIVE:to evaluate the diagnostic utility of elastography stain ratio in the assessment of solid solitarythyroid nodules.PATIENTS AND METHODS:a cross-sectional study was conducted on 65 selected patients with solid solitary thyroid nodulesdiscovered on Ultrasound (U/S) examination. The study was conducted in the U/S unit of medicalcollege/ Al-Nahrain university and U/S unit of Al-Imamein Al-Kadhimein Medical city in Baghdadduring the period from February 2018 to October 2019. U/S findings (size, shape and echogenicityof the nodules, presence of calcification, elastography findings and measurement of stain ratio), andhistopathological results of the FNA.RESULTS:the final histopathological diagnosis of the 65 thyroid lesions revealed 46 (71%) benign and 19(29%) malignant. Of the 19 malignant nodules; 12 were papillary carcinoma and 7 were follicularcarcinoma. The mean age of the patients was 43.7 ±11.7 years (range 28 - 60) years, 50 (77%) ofthem were female and 15 (23%) were male, male: female ratio is 5:1. Strain ratio (SR) of Benignnodules was lower than that of malignant nodules (1.95±0.62 versus 6.11±3.4) and this differencewas statistically significant (P- value <0.001. Best SR Cutoff - value was (>2.6) with a sensitivity of100% & specificity of 86.4% (a higher value was more indicative of malignancy).CONCLUSION:SR in a good parameter to aid differentiating benign from malignant solitary thyroid nodule. SR ishigher in malignant thyroid nodules.