Assessment of interleukin -10 and interferon-gamma with oral squamous cell carcinoma patients compared with healthy subjects as a prediction for early detection and monitor treatment response

Abstract

Background: In the worldwide oral squamous cell carcinoma (OSCC) is considered to be one of the most deadly diseases, due to it is late in diagnosis and absence of availability of established reliable biomarkers. The aim of current study was designed to detect cytokines in saliva of patient with oral squamous cell carcinoma and compared their levels with the healthy subjects and evaluate their validity as diagnosis and investigated changes of cytokines level in saliva pre-and post- surgical treatment to provide knowledge for exploring the use of saliva to monitor treatment response.