Synthesis , Chalcone and Study of the Biological Activity for Different Heterocyclic Compounds from the Chalcone Derivative


This study included preparation and characterization of the chalicon compound that which prepared fromreaction terephthalaldehyde with 4-bromoasetopheone and also prepared a number of heterocyclic compounds fromthe chalicon derivative with (Thiourea), (urea), (2,4-dinitrophenyl hydrazine),( 1,2-diamine-benzene) thesedreivatives are (Thiazine, Oxazine, Pyrazole, diazepine). All the prepared compounds were diagnosed by means ofthe FT-IR spectra and the proton 1H.NMR spectra. Then the bio-activity of these compounds and their effect on twotypes of bacteria (staphylococcus, Escherichia coli) were studied some compounds were identified that have a stronginhibitory effect.