Evaluation of liver functions in anemic and healthy dogs

Abstract

Most the Liver affections detected at a late stage for anemic K9 (police dogs) and they are very important to estimate liver functions to disclose diseases.To study liver function in dogs, chose forty five K9 dogs from Basrah and Maysan province- south of Iraq, the first group of thirty five dogs affected with anemia and second group of ten dogs appeared clinically normal served as control. The clinical findings and blood parameters directed for anemia detection then serum levels of liver functions were estimated. The anemic dogs displayed pale mucous membranes, depression, dehydration, loss of appetite, lethargy, and weakness, moreover, tachycardia was evinced. The hematological parameters in anemic dogs revealed decreased in total RBCc, Hb and PCV, as well as reduction of MCV and MCHC in concerning microcytic hypochromic anemia (P<0.05).The differences of activity of liver functions between anemic and normal dogs were reported, in the anemic group was increased activity of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphates (ALP), and bilirubin levels with significant importance than normal group (P<0.05). Other indicators included lowering levels of total protein and albumin in anemic dogs which were also significant (P<0.05). Anemic dogs showed changes in liver functions which are characterized by increased levels of ALT, AST, ALP, and bilirubin as well as decreased protein and albumin than normal, and associated signs of pale mucous membranes, depression, anorexia, and lethargy