Estimation of Serum Uric Acid, Urea and Creatinine in Essential 152 Hypertensive Patients

Abstract

Hypertension is one of the most common world disease, which caused many effects on human body. Renal dysfunction is one of the most important adverse effects of the hypertension, which can be studied by measurement of clinical biochemical parameters in blood. In the current study serum uric acid, urea and creatinine had been measured in blood of 82 hypertensive patients including ( 45 males & 37 females ), and 43 apparently healthy volunteers as control group, in order to identify the effect of hypertension on some renal function test such as serum uric acid, urea and creatinine in comparison with control group and compared these parameters between male and female hypertensive patients. From the data collected it found there are a significant increase in the mean values of serum urea and creatinine in hypertensive patients compared with control , while no significant difference in serum uric acid between hypertensive patients and control group. The results of comparison between male and female hypertensive patients for serum uric acid , urea and creatinine showed that there was a significant increase in mean value of serum uric acid in male than that in female hypertensive patients and no significant change was found in the mean values of serum urea and creatinine between male and female hypertensive patients.