The use of scorad index in clinical assessment of atopic dermatitis in children

Abstract

Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that occurs in persons of all ages but is more common in children. To determine the use of scorad index in clinical assessment of atopic dermatitis in childen, a descriptive study carried on pediatric patients visiting asthma and allergy center and department of dermatology in Tikrit Teaching Hospital from March 2007 to August 2007. At enrolment, they all underwent; full history, clinical examination, blood sampling; Total WBC count, eosinophil cells count (100), total serum IgE level (32) were determined. This study includes (100) patients with AD; 58 cases (58%) males and 42 cases (42%) females. Most of the patients get the AD in the first year of life, 62 cases (62%). The family history is positive in, 84 cases ( 84%). Most of the patients develop mild AD, 52 cases ( 52%). There was significant association between severity of AD according to scorad index (S.I) and type of infant feeding, the mean severity score (S.S) for the breast feeding (B.F) children were (21.48+4.96 ), while the mean S.S for the formula fed (F.F) children were (35.70+9.79). There was significant association between the age of onset of patients and type of infant feeding, the mean age of onset for the breast fed patients were (22+16.21 ), while the mean age of onset for the formula fed patients were (12.3+12.86). ). There was significant association between severity of AD and the family history, the mean S.S for the AD patients with strong positive family history was (37.3+ 11.84), while the mean S.S of AD patients with negative family history was (22.6 + 5.12). There was significant association between the hematological parameter of disease activity (total serum IgE, eosinophil count) and clinical activity(severity) of the disease measured by scorad index. Conclusion the study highly recommends the use of scorad index in clinical assessment of children with topic dermatitis.