Seroepidemiological study of Toxoplasmosis among pregnant women in Salah –Adden government.

Abstract

Toxoplasma gondii is worldwide distribution varies from 7% to 52.3% and causes several complications during pregnancy such as abortion especially in first trimester and congenital malformation. The present study is aimed to determine seroprevalence of Toxoplasmosis among pregnant women and to assess the relation of abnormalities and infection with Toxoplasma gondii, we tested 226 pregnant women had single or multiple fetal loss, for several reasons, 66(29.2%) of pregnant women had Toxoplasmosis. All women were examined for presence of Toxoplasma agglutination test and specific IgG and IgM antibodies by enzyme-linked immunofluorescent assay. Antitoxoplasma IgG indicate old or chronic infection was 59(26.1%) of cases while IgM antibody indicate recent or acute infection was 7(3.1%) of cases. Toxoplasmosis still considered one of the risk factors for fetal loss, so that serodiagnosis should be recommended to distinguish acute and chronic infection by determining the level of IgM and IgG antibody not only in pregnant women but even unmarried women as a routine test.