Evaluation of Serum Alanine aminotransferase, Aspartateaminotransferase and Alkaline phosphatase in Adult ObeseNinava People.


Obesity is a well known cause of a lot of health problems, these problems can be
further evaiuated by biochernical studies. In the present study 3 biochemical
parameters represented as: Alanine aminotransferase (ALT), Aspaftate
aminotransfetur. leSf; and Alkaline phosphatase (ALP) has been measured in blood
of 69 apparentiy healthy obese subjects (30 males& 39 females) which divided into
two subgroups according to body mass index (BMI) (30- 34.9) & (35- 39.9). The
control groui in"tuded 32 apparently healthy with normal weight subjects. The aim
of this research is to study the effect of obesity on the activity of aminotransferase
enzymes (ALT& AST), and alkaline phosphatase (ALP) in Ninava compared to
.o,1irol group (sr-rbjects with normal weight), in addition, to study the biochemical
changes of these enzymes within obese group which classified according to the BMI
and sex. According to the results which recorded in this study, there was a significant
increase in the activity of ALT, AST, and ALP in obese subjects when compared to
controls, also there is no significant effect of BMI on these enzymes in obese group
rvith a higher mean activities of three enzymes in class II obese group (BMI 35- 39 '9).
The results also showed no significant difference between male and female in obese
subjects for the mean activities of these enzymes.