GREEN APPROACH FOR IRON OXIDE NANOPARTICLES SYNTHESIS: APPLICATION IN ANTIMICROBIAL AND ANTICANCER- AN UPDATED REVIEW

Abstract

Cancer and microbial infections create numerous challenges nowadays. Chemotherapy agents cause severe side effects, while microbial infections, especially multidrug-resistant bacterial strains hard to treat with available antibiotics.Therefore, this review provides an overview of the green synthesis of Iron oxide nanoparticles (IONPs) with theirphysicochemical properties and mechanism of action. The IONPs causes cytotoxicity and antimicrobial activity bycausing oxidative distress through the production of Reactive Oxygen Species (ROS). The IONPs as an anticancer andantimicrobial agent may help to overcome the limitation of conventional treatments but needs toxicity evaluation beforeusage in clinical applications.