Level of Interleukin–8 in the Sera of Asthmatic Patients in Baghdad


Asthma is a common, chronic inflammatory, anaphylactic hypersensitivity disease .It is a world-wide distributed with a range extends from mild to severe fatal episodes. Fifty eight asthmatic patients sera have been collected from Al-Zahra'a consultant for asthma and allergy , during the period between July / 2008 – September / 2008 and thirty two sample of healthy peoples as a control group .The patients age ranged from ( 12-45 ) years .Enzyme linked immunosorbent assay ( ELISA) has been applied estimation of interleukin – 8(IL-8).The results showed that highly significant differences (P < 0.0001) between asthmatic patients – positive IL–8 and asthmatic patients – negative IL-8. There are no significant differences between residency (urban and rural regions) and levels of IL-8. There is a good relation between body mass index (BMI) and asthmatic patients (P < 0.005), but no relation between body mass index and levels of IL-8.