Effects of the Aqueous Extract of the of Cinnamonum zeylanicum Barks (Cinnamon) on Glucose, Haemoglobin and Lipid Profile in Alloxan – Induced Diabetic Rats


AbstractCinnamonum zeylanicum (cinnamon) bark is considered extensively in the endogenous system of medicine as a drug for diabetes in many countries . The current investigations focuses attention on the glucose and lipid lowering effect of the aqueous extract of Cinnamonum zeylanicum (cinnamon) barks on experimentally induced diabetes in rats . The biochemical parameters studied were plasma glucose, insulin , total cholesterol, triglycerides, phospholipids, mhaemoglobin, and glycosylated haemoglobin. In addition to measuring body weight , renal glucose reassertion were notified. Aqueous extract of cinnamon barks were orally administered daily for 30 days in a dose of 100 mg / kg body weight to alloxan– diabetic rats, and a significant reduction in the parameters measured was investigated compared to diabetic rats, meanwhile , Glibinclamise was used as standard reference drug. In conclusion cinnamon barks posses a hypoglycaemic with concurrent hypolipidemic effect in diabetic states , and may further suggests that cinnamon parks may be useful in the therapy and managements of diabetic hyperlipidemia through reducing lipids levels.