Chronic Renal Failure in Children Admitted to Children Welfare Teaching Hospital


ABSTRACT:BACKGROUND:Chroic renal failure (CRF) is a devastating medical, psychological, social and economic problem forpatients and their families.AIM OF THE STUDY:The aim of the present study was to determine the etiology, clinical presentations and highlighttreatment modalities used for patients with CRF admitted to children welfare teaching hospital.PATIENTS' AND METHODS:A Retrospective study of all children with CRF admitted to children welfare teaching hospital duringthe period from 1stof jan.2002 to 1st of jan.2007 were included in the study .CRF was defined ashaving glomerular filtration rate less than 80m1 /min/1.73m2.RESULTS:The study group included 50 patients with CRF below 17 years of age,29(58%) males and 21(42%)females. Male: female ratio 1.38:1Their age ranged between (1m -17 year).Twenty (40%) patients were above 10 years of age. In thisstudy the mean glomerularFiltration rate was (29.5 + 18.5m1 /min/1.73m2).Congenital abnormalities were the major cause of CRF, it was found in 18 patients (36%), followedby hereditary conditions in 14 (28%) patients and glomerular diseases in 13 (26%) patients.The most common presenting symptom was anemia. It was found in 16(32%) patients followed byhypertension in 12 patients (24%) and failure to thrive in 12(24%) patients.Twenty-one patients (42%) received peritoneal dialysis, four (8%) received hemodialysis. Renaltransplant was done to 3 patients (6%).CONCLUSION:Congenital abnormalities was to the most common cause of CRF in our patients. Establishing registrysystem that provide detailed information concerning the incidence, causes, and overall outcomes ofmild to severe renal functional impairment acquired during developmental age can clarify further thenatural history of the disease and the factors that influence its course.