THE EFFECT AQUEOUS EXTRACT OF THE LEAVES OF EUCALYPTUS GLOBULES ON CLINICAL LABORATORY PARAMETERS IN ALLOXAN – INDUCED DIABETIC RATS

Abstract

Eucalyptus globules leaves is considered extensively in the endogenous system of medicine as an antidiabetic agents in many countries . The current investigations focuses attention on the glucose and lipid lowering effect of the aqueous extract of E. globules leaves on experimentally induced diabetes in rats . The biochemical parameters studied were plasma glucose , insulin , total cholesterol , triglycerides , phospholipids , haemoglobin , and glycosylated haemoglobin . In addition body weight and renal glucose reabsorption were notified . Aqueous extract of E. globules were orally administered daily for 30 days in a dose of 150 mg / kg body weight to alloxan – diabetic rats , and a significant reduction in the parameters measured was investigated compared to diabetic rats , meanwhile , Glibinclamise was used as standard reference drug . In conclusion , E. globules leaves posses a hypoglycaemic with concurrent hypolipidemic effect in diabetic states , and may further suggests that E. globules may be useful in the therapy and managements of diabetic hyperlipidemia through reducing lipids levels .