Lipid profile and pre – eclampsia

Abstract

Objective: To assess if there are changes in lipid profile in pre-eclampsia and if these changes can be used as marker of severity of the condition.Study design: This study include 100 pregnant women divided into 3 groups.1) 25 pregnant women with sever pre-eclampsia in the third trimester.2) 25 pregnant women with mild-moderate pre-eclampsia in the third trimester .3) 50 apparently healthy pregnant women of comparable age &parity in the third trimester.All were investigated for serum lipid profile includingserum cholesterol(CH)serum triglyceride(TG)serum high density lipoprotein(HDL)serum low density lipoprotein(LDL)serum very low density lipoprotein(VLDL)Result: There was significant increase in serum TG ,VLDL and LDL level in women with pre -eclampsia than the control group and no significant difference in the serum cholesterol, while patient with pre-eclampsia had lower HDL level. When we compare patient with sever pre-eclampsia with patient with mild pre - eclampsia we found that women with sever pre -eclampsia has significantly higher level of TG and VLDL only.