Clinical Usefulness of IgE as a Serological Marker for Diagnosis of Nodular Scabies in Diyala Province

Abstract

This study designed to evaluate the clinical usefulness of IgE as a serological marker for diagnosis of nodular scabies.Sixty eight patients suffering from nodular scabies and twenty apparently healthy subjects as control group were included .The mean age of patients group was ( 31.67±1.67)years compared with (33.5 ±2.27) years in control group .Among patients group, males represent(76.5%) compared with (23.5%) females. Among control group males represent (55%) versus (45%) females .The mean of IgE concentration among control group was (59.25 ± 5.36 U/ml) compared with (160.16 ±16.78 U/ml )among patients group with statistical significant difference (p>0.05 ).In (34/ 68) of scabietic patients, the concentration of IgE was lower than cutoff concentration with the mean (46.23 ±5.09IU/ml ).The rest (34/ 68) scabietic patients have elevated concentration of IgE(274.08 ±18.18IU/ml ).There was a statistical significant difference (p>0.05) between patients groups in IgE concentrations.This study concludes that the diagnostic value of IgE as a serological marker cannot be considered as a single parameter for diagnosis of nodular scabies without clinical manifestations. This study proved that the serological concentration of IgE not necessarily elevated in all cases of nodular scabies