Estimation of thyroid hormones concentrations and some related hormones in normal and threatened abortion pregnancy in women in Tikrit city

Abstract

This study goaled to show the relationship between thyroid gland hormone concentrations Triiodothyronine (T3), Thyroxine (T4) and the incidence of threatened abortion pregnancy. the changes in Estrogen (E), Prolactin (PRL) and Thyroid Stimulating Hormone (TSH) were also investigated. The work performed through using 280 blood samples taken from women (15---36 years age) , attended Tikrit Teaching Hospital and some private medical clinc s. The results revealed a significant increase (p < 0.01) in the concentration of thyroid hormones ( T3, T4 ) in the normal pregnant women ,for all the pregnant months, when compared with the control group. A significant decrease ( p < 0.01) was also detected in the abortive threatened pregnancy women (ATPW), when compared with control group women , regarding T3 and T4 hormones concentration for the first four months of pregnancy. Non significant difference between the normal pregnant women group and the control group. It was evident that TSH concentration increase significantly ( p < 0.01 ) in the (ATPW) for the first four pregnancy months when compared with the control group women. Estrogen hormone concentration was found to be higher significantly ( p < 0.01) in the normal pregnant women for all pregnancy months as compared with the control group women. On the contrary a significant decrease in the estrogen hormone concentration in (ATPW) for the first four pregnancy months was found when compared with the control group. Prolactin was found to be higher significantly (p < 0.01) in both the normal pregnant women and the (ATPW)for all the pregnancy months pregnant women when compared with the control group.