Synthesis of Some Cyclohexene Derivatives by Diels-Alder Reaction

Abstract

In this study a compounds of 1-(4-chlorophenyl)-5-phenyl-4-methyl-2,4-pentadiene-1-one (1) and 1-(4-methoxyphenyl) -5- phenyl-4-methyl-2,4-pentandiene-1-one (2) were prepared by reaction of -methyl cinnamaldehyde with substituted acetophenones.Also1,3-diphenyl-2-chloropropene-1-one (3) was synthesized from reaction of benzaldehyde with 2-chloroacetophenone through Claisen - Shmidt condensation. The substituted cyclohexene (4,5) were prepared by reaction of (1,2) with (3) through Diels-Alder reaction. Compounds (4,5) were reacted with some of amino derivatives to synthesize compounds (6-11).The structures of all synthesized compounds were confirmed by available physical and spectral data.